They are not sure if it gets integrated in our DNA or not. Curr Issues Mol Biol. Both LT recipients and HCWs who had developed SARS-CoV-2 infection before vaccination, patients aged under 18, and patients who A clip being shared online in recent days shows three doctors, who have spread misinformation about the vaccines in the past, discussing the Swedish study and falsely claiming it demonstrates that the Pfizer vaccine reverse transcribes and installs DNA into the human genome, leading to harmful effects. shakira. A new Swedish study published in MDPIfound that the Pfizer vaccine goes into liver cells and converts to DNA, challenging claims so far that the mRNA COVID-19 vaccines do not change or interact with your DNA in any way. These cells have had the normal protections of the immune system removed.. In the March 2022 issue of Parents PACK, we discussed some common misconceptions about science and scientists, and in the April 2022 issue, we discussed some surprising findings that were initially not believed but were ultimately proven to change our previously established understanding of science. 2020;586:589593. The authors of a Swedish study said their study could not be used to draw conclusions with human DNA as they used cell lines in a laboratory petri dish for their work. Accessibility Front Immunol. Second, they measured LINE-1 activity. The content provided in this video is for informational and educational purposes only.\rPlease consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. :\rBuy me a coffee :-) https://www.buymeacoffee.com/DrMobeenSyed\rBecome my patron: https://www.patreon.com/mobeensyed?fan_landing=true\rPayPal: https://paypal.me/mobeensyed?locale.x=en_US\r\r#drbeen #koolbeens #COVID\r\rDisclaimer:\rThis video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. WebClaim : Pfizer COVID-19 Vaccine Changed DNA In Liver Cells! We have a new vaccine, and it needs to be tested in cell and animal models and also in humans, in various ways. The. Antibody levels were also measured in separate tests. As such, finding similar stretches of genes is not novel, unlikely, or particularly surprising. Accessibility statement. Data, especially data from vaccinated humans, will hopefully sort out the question marks. An important thing to notice when looking at this figure is that unlike most axis numbers, those on the y-axis showing cycle threshold are decreasing in number as they go higher on the graph. N. Engl. Apart from any fair dealing for the purpose of private study or research, no And yet, it has become commonplace for anti-vaccine activists to refer to the mRNA vaccines as gene therapy. The author described two potential mechanisms by which this could occur. It is reverse transcribed by LINE-1 proteins of the cells. Shakira. These tools for evaluating information may be useful: Categories: Available online: Mulligan M.J., Lyke K.E., Kitchin N., Absalon J., Gurtman A., Lockhart S., Neuzil K., Raabe V., Bailey R., Swanson K.A., et al. In this case, the author compared gene sequences to identify sections of human proteins that have portions similar to SARS-CoV-2 proteins and made a prediction that the similarities would cause immune responses against oneself. CLAIM: A Swedish study shows that Pfizers COVID-19 vaccine changes recipients DNA. CLAIM: A Swedish study shows that Pfizer's COVID-19 vaccine changes recipients' DNA. Redirecting to https://www.eviemagazine.com/post/is-mrna-therapy-the-new-botox Drugs and Lactation Database (LactMed) [Internet]. This will lead to some parts of our website to not work properly or at all. Life need not ever end Depressing established scientific idea may be wrong, New interpretations of the laws of thermodynamics suggest the infamous heat death hypothesis which foretells the end of all life in the universe might not hold Read more , Italy passes law to clamp down on illegal migration, stop and fine NGO rescue ships Analysis, It takes courage to enforce rule of law Read more , PM Mitsotakis said a cross-party committee would investigate the train crash causes, Mitsotakis made an extraordinary statement on TV Read more , Author:Thema Newsroom | Published: March 2, 2022, , , . in petri dishes, the researchers added Pfizer BioNTech's vaccine to a cell line that originally came from a human liver tumour. Finally, only looking at figure 1 dismisses the other data in the paper, such as the fact that people who were vaccinated were more likely to be asymptomatic and unvaccinated people tended to be more severely ill compared with vaccinated people. ADE is a condition in which the antibodies against a pathogen increase the ability of the pathogen to get into cells. But keep in mind, when the mRNA or adenovirus particles do hit cells outside of the liver or the site of injection, they're still causing them to express Spike protein anchored on their surfaces, not dumping it into the circulation. This means that what is seen in these cells may not be representative of what would happen in non-cancerous liver cells (or even a different line of cancerous liver cells). Huh7 cells, Detection of DNA amplicons of BNT162b2 in Huh7 cells treated with BNT162b2. doi: 10.7759/cureus.32361. The paper does not provide such evidence. and transmitted securely. It is known from animal studies that it is also expressed early in embryonic development", explains Yang de Marinis. Pfizer Vaccine Becomes DNA in Liver Cells. Suggested accounts. Bethesda, MD 20894, Web Policies Our COVID-19 vaccine does not alter the DNA sequence of a human cell, a Pfizer spokesperson told The Epoch Times in an email. It is known from animal studies that it is also expressed early in embryonic development," explains Yang de Marinis. The Centers for Disease Control and Spike proteins may circulate in the body after an infection or injection with a COVID-19 vaccine. Our monetization model empowers Citizen Journalists to report the news in local and national markets. Likewise, proteins from pathogens are sometimes going to share similar stretches with our proteins as well. Spetzofai is a rustic spicy Greek dish that is made with thick sausages and long green and red peppers in a rich tomato sauce. Lund University 1 . YDM: About 18 percent of the vaccine accumulates in the liver just 30 minutes after the vaccine is injected in mice as reported by Pfizer in EMA assessment report, and therefore we chose to study liver cells. Huh7 cells were treated without (Ctrl) or with 0.5, 1, and 2 g/mL of BNT162b2 for 6 h. Cells were fixed and stained with antibodies binding to LINE-1 ORF1p (red) and DNA-specific probe Hoechst for visualization of cell nucleus (blue). We saw that there was DNA converted from the vaccine's mRNA in the host cells we studied. MR: One should consider that cell lines differ from cells in living organisms, and therefore it is important that similar investigations are also studied in humans. Chia PY, Ong SWX, Chiew CJ, et al. The perfect family meal is here with healthy peas and beef full of protein! Markus Aldn et al, Intracellular Reverse Transcription of Pfizer BioNTech COVID-19 mRNA Vaccine BNT162b2 In Vitro in Human Liver Cell Line, Current Issues in Molecular Biology (2022). Bad Bunny. It is the three-dimensional (3D) structure. Errors in interpretation can come from biased authors, lack of understanding of the science or the scientific methodology, or even a decision to intentionally misrepresent the work. in Our publication is the first in vitro study on the conversion of mRNA vaccine into DNA, inside cells of human origin. Differences in IgG Antibody Responses following BNT162b2 and mRNA-1273 SARS-CoV-2 Vaccines. J Transl Autoimmun. According to Swedish researchers at Lund University, the messenger mRNA from Pfizers Covid vaccine can enter human liver cells and is converted into DNA. :\rBuy me a coffee :-) https://www.buymeacoffee.com/DrMobeenSyed\rBecome my patron: https://www.patreon.com/mobeensyed?fan_landing=true\rPayPal: https://paypal.me/mobeensyed?locale.x=en_US\r\r#drbeen #koolbeens #COVID\r\rChapters00:00 introduction00:45 Link to the summary01:00 Review of the reference material02:19 Cell preparation for the vaccine03:35 Vaccine addition to the cells06:00 RT-PCR for find RNA and then DNA13:39 Imaging of the cells and the LINE-1 protein, ORF-1 protein, and the DNA18:27 Measuring the volume of proteins in the cytosol and the nucleus22:35 DNA purification and verification28:41 Results28:42 LNP enters the liver cells efficiently29:33 LINE-1 gene is expressed30:46 ORF-1 found in cytosol and the nucleus36:01 DNA from the vaccine found in the cell43:30 Questions not answeredDisclaimer:\rThis video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. However, to someone trying to discern if the paper says what others are suggesting it says, a comparison of the methods and results sections with the subheadings used in the discussion section will quickly reveal that the topics addressed in the discussion go well beyond discussing protein sequences. (In-vitro Swedish Study) https://youtube.com/live/MjxlvduyJyc?feature=share 28 Feb 2023 02:39:58 2022;44(3):1115-26. You can unsubscribe at any time and we'll never share your details to third parties. WebThe Pfizer/BioNTech COVID-19 vaccine uses a fragment of messenger RNA (mRNA) to instruct your body to make an immune response against COVID-19. DNA amplicons (444 bps) were visualized on agarose gel. Evaluating information: What you should know, Dissecting social media: What you should know. Three other points about this paper are worth noting: Misclassification of study and logical fallacies (hasty generalization and appeal to ignorance). Likewise, the Results section has five sentences. These insects are generally larger in temperate areas than in the tropics. The Japanese regulatory agencys biodistribution study (pdf) of the Pfizer vaccine showed that some of the mRNAs moved from the injection site and through the bloodstream, and were found in various organs such as the liver, spleen, adrenal glands, and ovaries of rats 48 hours following injection. Fax: +46 (0)46 222 47 20, Invoice address: Box 188, 221 00 Lund APS ASSESSMENT: False. The results have been widely discussed across social media but the results have in many cases been misinterpreted. Epub 2022 Feb 3. To understand why this is unlikely, one needs to know a bit about protein chemistry: An analysis like the one in this paper may allow one to create an interesting hypothesis, but it does not provide evidence of a concern. Salesforce Reportedly Pays Matthew McConaughey $10 Million A Year Despite Massive Employee Layoffs Last Month, The Boring Company CEO Is Set To be The Next CEO Of Twitter, OH city violates state pre-emption, carjackings explode in NOLA, Canada hates US gun laws. Moore also cautioned that the cells used in the study were quite different than primary cells in the body. The cell line came from liver cancer cells, which means their replication mechanisms were more active, and amplified the process in a way that would not have happened in healthier human cells, Moore said. FOIA Chicks also weigh less the more non-native trees there are, The size of dragonflies and damselflies varies around the globe. More than 215 million or 64.9 percent of Americans are fully vaccinated as of Feb. 28, with 94 million having received a booster dose. Does the Pfizer-BioNTech mRNA vaccine get converted to DNA or not? BNT162b2 mRNA levels in Huh7 cells treated with BNT162b2. They certainly tell us something we did not know without the study, but it is important to understand the limitations of the data. Pfizer didnt comment on the findings of the Swedish study and said only that its mRNA vaccine does not alter the human genome. Huh7 cells were treated, Immunohistochemistry of Huh7 cells treated, Immunohistochemistry of Huh7 cells treated with BNT162b2 on LINE-1 protein distribution. Webpfizer vaccine become dna in liver cells 449M views Discover short videos related to pfizer vaccine become dna in liver cells on TikTok. Finally, protein shapes change in different environments, so while it may be interesting to compare in which parts of the body these proteins with similar stretches are located, we cant really know whether cross-reactivity would be an issue simply by comparing the gene sequences or even by working with the proteins on the lab bench. In the study, the authors infected a human liver cell line with the Pfizer version of the COVID-19 vaccine. (In 2022 Dec 9;14(12):e32361. The blood samples were analyzed for the virus that causes COVID-19 by subjecting them to polymerase chain reaction (PCR) testing. MR: The study was performed on human liver cells from one cell linecell cultures used for research purposes. The whole process of Pfizers mRNA transfecting liver cells occurred within just six hours, per the study. Said another way, it was an . MR: There is no reason for anyone to change their decision to take the vaccine based on this study. We have a new vaccine, and it needs to be tested in cell and animal models and also in humans, in various ways. HHS Vulnerability Disclosure, Help how to get soul star bosses of mass destruction, what is a decision day for drug testing, Going to share similar stretches of genes is not novel, unlikely, or particularly surprising of human origin proteins. Pathogen to get into cells of human origin LINE-1 proteins of the data vaccine! 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